The current study to investigate the antimicrobial potential of Pedalium murex L plant. Fresh plants with authentication were selected for antimicrobial assays. Extract of stem and stem bark was extracted in hexane by means of a Soxhlet device. It was then undertaken for determination of antimicrobial activity against bacteria such as Candida albicans, Staphylococus Aureus, Escherichia coli, K.pneumoniae, P.aeruginosa and B.subtilis. MIC was found to be 15mg/ml at this concentration stem bark extract showed remarkable antibacterial activity as compared to stem extract and their zone of inhibition compared with standard antibiotics. The bacterial strain of S. aureus and E. coli showed 17mm and 22mm zone of inhibition respectively that of ampicillin and streptomycin showed very less inhibition. Stem bark also sensitive to yeast fungus Candida albicans, reported a 16mm zone of inhibition, which was moderate as compared to fluconazole. Phytochemical screening of extract showed presence of steroid and triterpenes. Thus, the current investigation leads to fresh sources of new antimicrobials in future. This is the first report in vitro this revealed medicinal importance of ornamental plant Pedalium murex.
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